Do NOT use Advair Diskus Powder if:
- you are allergic to any ingredient in Advair Diskus Powder or to milk proteins
- you are having an asthma attack or severe breathing problems (eg, sudden, severe onset or worsening of asthma or COPD symptoms, such as chest tightness, cough, shortness of breath, wheezing)
- you are using another type of long-acting inhaled bronchodilator (eg, formoterol, salmeterol)
- you are taking an azole antifungal (eg, itraconazole, ketoconazole), a certain HIV protease inhibitor (eg, atazanavir, indinavir, ritonavir), a macrolide antibiotic (eg, clarithromycin), nefazodone, or telithromycin
- you have asthma that is already well controlled with the use of a long-term asthma-control medicine (eg, inhaled corticosteroid)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Advair Diskus Powder:
Some medical conditions may interact with Advair Diskus Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of diabetes, eye problems (eg, cataracts, glaucoma, increased pressure in the eye), heart problems (eg, fast or irregular heartbeat, heart blood vessel problems), high blood pressure, nervous system problems, liver problems, low blood potassium levels, high blood acid levels (eg, ketoacidosis), seizures, thyroid problems, or an adrenal gland tumor
- if you are having a COPD flare-up, have recently been to an emergency room for asthma, have a history of frequent hospitalizations for asthma, or have ever had a life-threatening asthma attack
- if you have a fungal, bacterial, or parasitic infection; a viral infection (eg, measles, chickenpox, shingles); herpes virus infection of the eye; tuberculosis (TB); a history of a positive TB skin test; an immune system problem; or if you have had a recent vaccination
- if you have weak bones (osteoporosis) or have risk factors of osteoporosis (eg, a family history of osteoporosis, tobacco use, long-term use of corticosteroids or certain seizure medicines, limited physical exercise, poor nutrition)
- if you have had an unusual reaction to a sympathomimetic medicine (eg, albuterol, pseudoephedrine), such as fast or irregular heartbeat, overexcitement, or severe trouble sleeping
- if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or if you have taken either of these medicines within the last 14 days
Some MEDICINES MAY INTERACT with Advair Diskus Powder. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, hydrochlorothiazide, furosemide) or other long-acting inhaled bronchodilators (eg, salmeterol inhalation powder, formoterol inhalation powder) because the risk of low blood potassium or irregular heartbeat may be increased
- Beta-blockers (eg, propranolol) because they may decrease Advair Diskus Powder’s effectiveness
- Azole antifungals (eg, itraconazole, ketoconazole), catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), delavirdine, HIV protease inhibitors (eg, atazanavir, indinavir, ritonavir), macrolide antibiotics (eg, clarithromycin), MAOIs (eg, phenelzine), nefazodone, short-acting beta-agonist bronchodilators (eg, albuterol), telithromycin, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Advair Diskus Powder’s side effects
This may not be a complete list of all interactions that may occur. Ask your health care provider if Advair Diskus Powder may interact with other medicines that you take.